Species: Dog
Condition: Progressive Neuronopathy
Organ System: Nervous/sensory

A genetic disorder affecting nervous cells of the spinal chord and causing them to degenerate. It usually affects young dogs causing muscle weakness, incoordination and paralysis. Symptoms worsen with exercise. The dog is acquiring abnormal body positions, walks insecurely and seems uncoordinated. The condition progresses over a period of a few months to complete all four legs weakness and eventually complete paralysis. The vet will determine loss of reflexes and other neurologic abnormalities. Unfortunately, there is no available cure for this disease and it is best to put the dog to sleep when its quality of life deteriorates.

Breeds exposed to Progressive Neuronopathy – Research Reference
Chihuahua Cross – Canine Inherited Disorders Database (CIDD)
Rottweiler Cross – Canine Inherited Disorders Database (CIDD)
“Papillon Cross – (Franklin
Bullmastiff – Canine Inherited Disorders Database (CIDD)
Rottweiler – Canine Inherited Disorders Database (CIDD)
Chihuahua – Canine Inherited Disorders Database (CIDD)
Labradoodle – Canine Inherited Disorders Database (CIDD)
Labrador Cross – Canine Inherited Disorders Database (CIDD)
Bullmastiff Cross – Canine Inherited Disorders Database (CIDD)
Labrador Retriever Cross – Canine Inherited Disorders Database (CIDD)
Labrador – Canine Inherited Disorders Database (CIDD)
Labrador Retriever – Canine Inherited Disorders Database (CIDD)
“Papillon – (Franklin
Labradoodle Cross – Canine Inherited Disorders Database (CIDD)

Disease Author
Dr Merliza Cabriles, Professor of Veterinary Medicine

To learn more about Progressive Neuronopathy or any other condition we invite you to search this website. Even better, pick up the phone and call your vet. Your vet knows your pet better than anyone else and is a fountain of information.

This information is accurate as at May 2014 and is subject to change without notice.
For Petmed Pet Health Insurance – pre-existing condition exclusion applies. Annual Benefit Limits and excess amounts vary based on pet health insurance plans.

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