Species: Dog
Condition: Anesthetic Idiosyncracy
Organ System: Cardiovascular

An abnormal, unreliable response to commonly used anaesthetics. It is believed to be caused by the incapability of the liver to properly metabolise anaesthetic agents. In severe cases it can lead to cardiac and/or respiratory arrest during the surgical procedure with the danger of a fatal outcome. Unfortunately, this reaction is completely unpredictable and there is no certain way to predict or determine this kind of response. Anaesthetic idiosyncrasy is common in certain dog breeds. In case of surgery, the vet will know what anaesthetic agents to use for them in order to avoid life threatening situations.

Breeds exposed to Anesthetic Idiosyncracy – Research Reference
Boston Terrier Cross – Canine Inherited Disorders Database (CIDD)
Cavalier King Charles Spaniel Cross – Canine Inherited Disorders Database (CIDD)
Lhasa Apso Cross – Canine Inherited Disorders Database (CIDD)
Boxer Cross – (Seeliger et al. 2003)
Pug Cross – Canine Inherited Disorders Database (CIDD)
French Bulldog Cross – Canine Inherited Disorders Database (CIDD)
St Bernard Cross – (Harrus et al. 2002)
Staffordshire Bull Terrier Cross – Canine Inherited Disorders Database (CIDD)
Shar-Pei Cross – Canine Inherited Disorders Database (CIDD)
Shih Tzu Cross – Canine Inherited Disorders Database (CIDD)
Pekingese Cross – Canine Inherited Disorders Database (CIDD)
Cavoodle – Canine Inherited Disorders Database (CIDD)
Boston Terrier – Canine Inherited Disorders Database (CIDD)
Cavalier King Charles Spaniel – Canine Inherited Disorders Database (CIDD)
French Bulldog – Canine Inherited Disorders Database (CIDD)
Lhasa Apso – Canine Inherited Disorders Database (CIDD)
Pekingese – Canine Inherited Disorders Database (CIDD)
Pug – Canine Inherited Disorders Database (CIDD)
Shar-Pei – Canine Inherited Disorders Database (CIDD)
Shih Tzu – Canine Inherited Disorders Database (CIDD)
Staffordshire Bull Terrier – Canine Inherited Disorders Database (CIDD)
“Bullmastiff Cross – (Seim 2001
British Bulldog Cross – (Hedlund 2003)
Cocker Spaniel Cross – Boydell P. (1995) (Idiopathic Horner?s syndrome in the golden retriever)
Spoodle Cross – Boydell P. (1995) (Idiopathic Horner?s syndrome in the golden retriever)
St Bernard – (Harrus et al. 2002)
British Bulldog – (Hedlund 2003)
Boxer – (Seeliger et al. 2003)
“Bullmastiff – (Seim 2001
Cocker Spaniel – Boydell P. (1995) (Idiopathic Horner’s syndrome in the golden retriever)
Spoodle – Boydell P. (1995) (Idiopathic Horner’s syndrome in the golden retriever)

Disease Author
Dr Merliza Cabriles, Professor of Veterinary Medicine

To learn more about Anesthetic Idiosyncracy or any other condition we invite you to search this website. Even better, pick up the phone and call your vet. Your vet knows your pet better than anyone else and is a fountain of information.

This information is accurate as at May 2014 and is subject to change without notice.
For Petmed Pet Health Insurance – pre-existing condition exclusion applies. Annual Benefit Limits and excess amounts vary based on pet health insurance plans.

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