Species: Dog
Condition: Alpha-1 Antitrypsin-related Hepatitis
Organ System: Gastrointestinal
Also called AAT Related Chronic Hepatitis, AAT Related Chronic Cirrhosis, Alpha-1 Anti-protease Deficiency, Alpha-1 Protease Inhibitor Deficiency, AATD. Alpha-1 antitrypsin is a blood protein predominantly synthesized in the liver. It functions to protect tissues from specific blood cells that kill bacteria when the body mounts an immune response. In AATD, there is the absence or low levels of the blood protein AAT in the blood resulting in tissue damage and swelling. Another potential condition that can take place is inflammation and/or cirrhosis of the liver caused by the accumulation of abnormal protein in the cells of the liver.
Breeds exposed to Alpha-1 Antitrypsin-related Hepatitis – Research Reference
“Golden Retriever Cross – (Brodey & Kelly 1968
“Boxer Cross – (Brodey & Kelly 1968
“Beagle Cross – (Brodey & Kelly 1968
“Beagle – (Brodey & Kelly 1968
“Boxer – (Brodey & Kelly 1968
“Golden Retriever – (Brodey & Kelly 1968
“Golden Doodle (Groodle) – (Brodey & Kelly 1968
Disease Author
Dr Merliza Cabriles, Professor of Veterinary Medicine
To learn more about Alpha-1 Antitrypsin-related Hepatitis or any other condition we invite you to search this website. Even better, pick up the phone and call your vet. Your vet knows your pet better than anyone else and is a fountain of information.
This information is accurate as at May 2014 and is subject to change without notice.
For Petmed Pet Health Insurance – pre-existing condition exclusion applies. Annual Benefit Limits and excess amounts vary based on pet health insurance plans.
